SAN FRANCISCO, November 15, 2026 — Anthropic’s AI lab has achieved a significant breakthrough in porting its Claude model to run on AMD’s MI355 GPUs, potentially undermining Nvidia’s long-standing software dominance in the AI chip market. This development comes as Anthropic prepares for its initial public offering, with a valuation expected to range from $1.1 trillion to $1.3 trillion.
Breaking Down Nvidia’s CUDA Moat
Nvidia’s CUDA platform, developed in 2005, has created a significant barrier to entry for competitors in the AI chip market. By training developers on its GPUs and making them the default for AI workloads, Nvidia has established a strong ecosystem that has been difficult for rivals to penetrate. However, Anthropic’s Claude Mythos Preview model has now successfully ported and optimized Claude to run on AMD’s MI355 GPUs in just three days, with Claude writing 100% of the kernels. This achievement suggests that Anthropic’s software could reduce reliance on CUDA, potentially opening doors for AMD’s MI355 GPUs in AI training.
Market Impact and Key Players
The implications of this breakthrough are significant, with AMD’s data center revenue growing 97% year over year to $8.5 billion in Q3. CEO Lisa Su has highlighted AI-related growth as a key tailwind for the company, and this development could further accelerate AMD’s growth in the data center market. Meanwhile, Nvidia has up to $20 billion invested in Anthropic, creating a potential financial conflict if Anthropic shifts its hardware preferences. Nvidia’s “You Only Live Twice” scandal may also erode investor confidence in its ecosystem, while AMD’s stock has seen a bounce after its Q3 earnings report.
What’s Next for Anthropic and the AI Chip Market
As Anthropic begins its roadshow ahead of a potential Nasdaq debut, the company will need to convince investors that its business model can withstand recent events and market volatility. With rival OpenAI filing to go public as soon as next year, Anthropic may need to capitalize on investor appetite for AI stocks before its competitor arrives. The question remains whether other AI labs will adopt Anthropic’s approach, or if Nvidia will counter with new software locks to maintain its dominance in the AI chip market. Anthropic’s roadshow is set to start this week, with the company’s IPO valuation and timing hanging in the balance.
Sources
- Anthropic Just Delivered Great News for AMD Investors and Bad News for Nvidia – AOL
- Anthropic Just Delivered Great News for AMD Investors and Bad News for Nvidia
- Anthropic Can Now Start Its Roadshow. The Traffic’s Bad.
- Lisa Su Just Delivered Fantastic News for AMD Investors
Photo: Fuzheado (CC BY 4.0)
